EZskew Instructions


EZskew calculates nucleotide biases along protein-coding genes of metazoan mitogenomes, avoiding manual errors. It computes:

  • A-T bias
  • Strand bias for J (light) and N (heavy) strands
  • Codon position bias for 1st, 2nd, and 3rd positions (including 2-fold and 4-fold degenerate codons, if required)
  1. Prepare separate FASTA files for genes on the J and N strands.
  2. Acceptable formats are: .fasta, .fa, .fsa, .fas, .fna, .ffn, .faa, .frn
  3. Name sequences consistently across genes and strands.
  4. Ensure only standard nucleotides or IUPAC ambiguity codes (IUPAC) are present.
  5. Gaps inside sequences will be removed automatically.

Upload Your Files


Drag & drop J gene FASTA files here
or click to select (multiple allowed)
Drag & drop N gene FASTA files here
or click to select (multiple allowed)

*If not provided, a random job ID will be assigned.